Table 2 Characteristics of the integrated data-base and FibroTest diagnostic value in liver disease
From: Meta-analyses of FibroTest diagnostic value in chronic liver disease
Disease | Number | Age yr | Biopsy Length mm | F0 (%) | F1 (%) | F2 (%) | F3 (%) | F4 (%) | ObAUROC | DANA | AdAUROC | High risk profile $ (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
HCV | 2,431 | 47 | 17 | 204 (8.4) | 1123 (46.2) | 531 (21.8) | 298 (12.3) | 275 (11.3) | 0.77 0.75–0.79 | 1.92 | 0.83 0.81–0.85 | 26/1681 (1.5) |
HBV | 322 | 42 | 17 | 86 (26.7) | 94 (29.2) | 61 (18.9) | 38 (11.8) | 43 (11.4) | 0.81 0.76–0.86 | 2.30 | 0.83 0.78–0.88 | 9/322 (2.8) |
ALD | 262 | 48 | 14 | 18 (6.9) | 67 (25.6) | 50 (19.1) | 23 (8.8) | 104 (39.7) | 0.85 0.80–0.89* | 2.52 | 0.85 0.80–0.89 | 5/262 (1.9) |
NAFLD | 267 | 51 | 19 | 102 (38.2) | 94 (35.2) | 35 (13.1) | 23 (8.6) | 13 (4.9) | 0.81 0.74–0.86 | 2.21 | 0.84 0.77–0.89 | 7/267 (2.6) |
All | 3,282 | 47 | 17 | 410 (12.5) | 1378 (42.0) | 677 (20.6) | 382 (11.6) | 435 (13.3) | 0.79 0.77–0.80 | 2.07 | 0.84 0.82–0.86 | 47/2,532 (1.9) |