Skip to main content

Table 3 Inhibition. Decreases in short circuit current (SCC) after inhibition with indometacin (40 μM), bumetanide (2.5 μM), ouabain (200 nM) and amiloride (100 μM).

From: Colonic epithelial ion transport is not affected in patients with diverticulosis

 

Compound

N, n

Median

Range

P value

Mean

SEM

   

μA·cm -2

μA·cm -2

   

Controls

Indometacin

14, 20

16.0

3.4–41.4

 

11.2

4.3

D-patients

Indometacin

3, 7

8.6

6.6–17.4

0.112

7.7

2.5

Controls

Bumetanide

12, 18

19.0

3.6–57.0

 

20.0

3.8

D-patients

Bumetanide

4, 8

18.9

9.6–38.5

0.475

20.2

4.5

Controls

Ouabain

20, 31

27.4

4.0–103.4

 

33.9

5.5

D-patients

Ouabain

8, 12

22.0

2.8–34.0

0.394

20.6

3.3

Controls

Amiloride

16, 28

6.5

2.0–40.0

 

11.9

2.1

D-patients

Amiloride

4, 15

8.0

1.6–27.4

0.475

8.8

1.9