Table 2 Stimulation. Increases in short circuit current (SCC) after stimulation with 5-HT (100 μM), forskolin (1 μM), theophylline (100 μM) and carbachol (10 μM).
From: Colonic epithelial ion transport is not affected in patients with diverticulosis
| Â | Compound | N, n | Median | Range | P value | Mean | SEM |
|---|---|---|---|---|---|---|---|
|  |  |  | μA·cm -2 | μA·cm -2 |  |  |  |
Controls | 5-HT | 12, 15 | 6.2 | 0.2–45.6 |  | 9.9 | 3.2 |
D-patients | 5-HT | 9, 14 | 4.9 | 0.2–20.2 | 0.807 | 7.2 | 1.7 |
Controls | Forskolin | 14, 19 | 18.6 | 0.1–109.0 |  | 26.8 | 7.0 |
D-patients | Forskolin | 9, 13 | 14.0 | 0.7–60.0 | 0.619 | 16.5 | 5.6 |
Controls | Theophylline | 20, 26 | 7.3 | 0.1–62.6 |  | 12.9 | 3.5 |
D-patients | Theophylline | 11, 13 | 7.8 | 0.3–36.8 | 0.572 | 12.9 | 3.1 |
Controls | Carbachol | 3, 9 | 12.2 | 4.8–46.6 |  | 18.1 | 5.7 |
D-patients | Carbachol | 3, 9 | 11.2 | 4.4–64.4 | 0.508 | 25.4 | 9.2 |