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Table 1 Five-hour total urine volumes (mL) and urinary recovery (%) of orally ingested lactulose (5 g) and L-rhamnose (0.5 g) in four experimental conditions (n = 33).

From: Effects of oral adenosine 5'-triphosphate and adenosine in enteric-coated capsules on indomethacin-induced permeability changes in the human small intestine: a randomized cross-over study

Experimental condition

Recovery (%)

Median (interquartile range)

Urine volume (mL)

Median (interquartile range)

 

Lactulose

Rhamnose

 

Control 1

0.14 (0.08–0.22)

4.41 (3.31–5.88)

298 (182–613)

Indomethacin + placebo

0.20 (0.11–0.31)*

4.60 (3.15–5.91)

324 (193–493)

Indomethacin + ATP

0.18 (0.12–0.32)*

4.12 (3.23–4.89)

371 (165–518)

Indomethacin + adenosine

0.23 (0.11–0.28)*

4.52 (3.90–5.26)

307 (213–563)

  1. 1No indomethacin, no placebo/ATP/adenosine
  2. Differences in lactulose/rhamnose recovery and urine volumes between the conditions with indomethacin plus placebo, ATP or adenosine were not significant
  3. *P < 0.01 vs. control (Wilcoxon signed ranks test)