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Table 2 Comparison of the sensitivity, specificity and predictive values of CP, MELD scores and serum AHSG in patients with alcoholic liver cirrhosis

From: Human serum fetuin A/α2HS-glycoprotein level is associated with long-term survival in patients with alcoholic liver cirrhosis, comparison with the Child-Pugh and MELD scores

 

(A) 1-year follow-up period

(B) Follow-up between months 1–12

CP score

  

AUC ± SD

0.865 ± 0.040

0.855 ± 0.050

p

< 0.001

< 0.001

95% C.I.

0.787 – 0.943

0.757 – 0.953

MELD score

  

AUC ± SD

0.739 ± 0.052

0.740 ± 0.058

p

< 0.001

0.001

95% C.I.

0.637 – 0.871

0.626 – 0.854

Serum AHSG

  

AUC ± SD

0.937 ± 0.025

0.908 ± 0.035

p

< 0.001

0.001

95% C.I.

0.889 – 0.986

0.839 – 0.978

CP score < 10, ≥ 10

  

Relative Risk

3.878

4.838

p

< 0.001

< 0.001

95% C.I.

1.998 – 7.527

2.009 – 11.649

Sensitivity at this cutoff value

0.753

0.675

Specificity at this cutoff value

0.827

0.755

MELD score < 20, ≥ 20

  

Relative Risk

2.205

2.4167

p

0.002

0.011

95% C.I.

1.318 – 3.689

1.229 – 4.952

Sensitivity at this cutoff value

0.595

0.587

Specificity at this cutoff value

0.729

0.720

AHSG < 365 μg/ml, ≥ 365 μg/ml

  

Relative Risk

9.874

9.257

p

< 0.001

< 0.001

95% C.I.

4.258 – 22.898

3.945 – 21.724

Sensitivity at this cutoff value

0.865

0.783

Specificity at this cutoff value

0.942

0.936

AHSG < 300 μg/ml, ≥ 300 μg/ml

  

Relative Risk

4.209

4.813

p

< 0.001

< 0.001

95% C.I.

2.675 – 6.622

2.813 – 8.233

Sensitivity at this cutoff value

0.594

0.478

Specificity at this cutoff value

0.981

0.972