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Table 1 The basal characteristics of the 6 patients included in the statistical analysis.

From: Effects of urodilatin on natriuresis in cirrhosis patients with sodium retention

  No. 1 No. 2 No. 3 No. 4 No. 5 No. 6
[unit/reference interval] Male Male Female Male Male Female
Total Plasma Bilirubin [< 22 micromol/L] 33 549 35 33 17 38
Plasma Albumin [551–725 micromol/L] 366 445 330 506 272 294
PP [0.80–1.20 arbitrary units] 0.55 0.20 0.30 0.66 0.42 0.39
Ascites yes yes yes yes yes yes
Encephalopathy no no no no no no
MELD score [5–15 points] 6 27 9 6 6 9
Plasma Sodium [136–146 mmol/L] 132 134 140 135 125 132
Plasma Creatinine [55–120 micromol/L] 105 50 62 85 52 58
Urine Sodium/24 hours [mmol/24 h] 10 35 27 48 35 31
UNa (baseline) [μmol/min] URO 3.1 Pl. 6.7 URO 28.1 Pl. 14.8 URO 36.7 Pl. 37.0 URO 22.5 Pl. 41.4 URO 44.0 Pl. 40.0 URO 18.7 Pl. 34,7
V (baseline) [mL/min] URO 0.44 Pl. 1.04 URO 0.35 Pl. 0.44 URO 1.20 Pl. 1.77 URO 0.74 Pl. 0.90 URO 1.18 Pl. 1.65 URO 0.93 Pl. 1.93
Serum Renin [10–70 mIU/L] 273 527 19 371 104 545
Serum Angiotensin II [10–30 pmol/L] 97 100 6 42 33  
Serum Aldosterone [40–500 pmol/L] 5363 1419 287 171 306 1768
Systemic Blood Pressure [mmHg] 95/60 112/65 100/60 112/65 105/80 100/65
Furosemide [mg/24 hours] 80 40 40 120 80 80
Spironolactone [mg/24 hours] 200 200 200 200 200 200
  1. URO = urodilatin. Pl. = placebo. UNa = urine sodium excretion rate. V = urine flow rate. PP = prothrombin time. MELD = Model of End-stage Liver Disease.