Figure 1

ROC curves of the FibroTest for the detection of advanced fibrosis in Group 1 and Group 2 (A), in the overall population (B), for bridging fibrosis or cirrhosis in Group 1 and Group 2 (C), and in the overall population (D). The diagonal line represents that achieved by chance alone (area under the curve 0.50); the ideal area under the curve is 1.00. Upper curve is Group1, lower curve is Group 2. There was no difference between the area under the ROC curves (AUROCs) for advanced fibrosis AUROC = 0.86 (95%CI 0.77–0.91) versus 0.75 (95%CI 0.61–0.83; P = 0.10), for bridging fibrosis or cirrhosis 0.92 (95%CI 0.83–0.96) versus 0.81 (95%CI 0.64–0.91; P = 0.12) in Group1 and Group 2 respectively. In the overall population the AUROCs for advanced fibrosis= 0.81 (95%CI 0.74–0.86) and for bridging fibrosis or cirrhosis = 0.88 (95%CI 0.82–0.92).