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Table 2 Observed numbers and crude odds ratios (ORs) of low-risk and advanced colonic neoplasia in association with various risk factors related to lifestyle (n = 3998)a.

From: Lifestyle as a predictor for colonic neoplasia in asymptomatic individuals

 

Controlsb (n = 3447)

Low-risk adenomas (n = 443)

Advanced neoplasia (n = 108)c

Lifestyles variablesd

n (%)

n (%)

OR [95% CI]

n (%)

OR [95% CI]

Gender

     

   Male

1642 (47.6%)

252 (56.9%)

Reference

67 (62.0%)

Reference

   Female

1805 (52.4%)

191 (43.1%)

0.69 [0.57–0.84]

41 (38.0%)

0.56 [0.38–0.83]

BMI (kg/m2)

     

   BMI<25

1630 (47.6%)

187 (42.2%)

Reference

47 (43.5%)

Reference

   BMI = 25–29.9

1392 (40.7%)

194 (43.8%)

1.22 [0.98–1.50]

44 (40.7%)

1.10 [0.72–1.66]

   BMI ≥ 30

399 (11.7%)

62 (14.0%)

1.35 [1.00–1.84]

17 (15.7%)

1.48 [0.84–2.60]

   

Ptrend = 0.02

 

Ptrend = 0.22

Smoking

     

   Never

1212 (35.3%)

123 (27.8%)

Reference

24 (22.2%)

Reference

   Former

956 (27.8%)

116 (26.2%)

1.20 [0.92–1.56]

24 (22.2%)

1.27 [0.72–2.25]

   Occasional

171 (5.0%)

25 (5.6%)

1.44 [0.91–2.28]

1 (0.9%)

0.30 [0.04–2.20]

   1–10 cigarettes/day

504 (14.7%)

71 (16.0%)

1.39 [1.02–1.89]

21 (19.4%)

2.10 [1.16–3.81]

   11–20 cigarettes/day

496 (14.4%)

92 (20.8%)

1.83 [1.37–2.44]

30 (27.8%)

3.05 [1.77–5.28]

   >20 cigarettes/day

97 (2.8%)

16 (3.6%)

1.63 [0.93–2.85]

8 (7.4%)

4.17 [1.82–9.52]

   

Ptrend < 0.001

 

Ptrend < 0.001

Total score for exercise with or without sweating

     

   Quartile 1 (score 2–4)

724 (22.1%)

99 (23.2%)

Reference

33 (31.1%)

Reference

   Quartile 2 (score 5)

502 (15.4%)

69 (16.2%)

1.01 [0.72–1.40]

14 (13.2%)

0.61 [0.32–1.16]

   Quartile 3 (score 6)

788 (24.1%)

93 (21.8%)

0.86 [0.64–1.17]

27 (25.5%)

0.75 [0.45–1.26]

   Quartile 4 (score 7–12)

1256 (38.4%)

165 (38.7%)

0.96 [0.74–1.25]

32 (30.2%)

0.56 [0.34–0.92]

   

Ptrend = 0.65

 

Ptrend = 0.04

Servings of vegetable, fruit and berries per day

     

   Quartile 1 (0–1.07 servings per day)

790 (24.1%)

108 (25.8%)

Reference

38 (36.9%)

Reference

   Quartile 2 (1.08–1.71 servings per day)

784 (23.9%)

114 (27.2%)

1.06 [0.80–1.41]

27 (26.2%)

0.72 [0.43–1.18]

   Quartile 3 (1.72–2.50 servings per day)

818 (24.9%)

109 (26.0%)

0.98 [0.73–1.29]

18 (17.5%)

0.46 [0.26–0.81]

   Quartile 4 (At least 2.60 servings per day)

889 (27.1%)

88 (21.0%)

0.72 [0.54–0.98]

20 (19.4%)

0.47 [0.27–0.81]

   

Ptrend = 0.03

 

Ptrend = 0.002

Consumption of boiled potatoes

     

   <1 time/week

234 (6.9%)

21 (4.8%)

Reference

9 (8.4%)

Reference

   1–3 times/week

1082 (31.9%)

121 (27.7%)

1.25 [0.77–2.02]

33 (30.8%)

0.79 [0.37–1.68]

   ≥4 times/week

2075 (61.2%)

295 (67.5%)

1.58 [1.00–2.52]

65 (60.7%)

0.81 [0.40–1.66]

   

Ptrend < 0.01

 

Ptrend = 0.75

Consumption of meat other than poultry

     

   <1 time/week

520 (15.4%)

55 (12.7%)

Reference

19 (18.3%)

Reference

   1–3 times/week

2325 (69.0%)

295 (68.1%)

1.20 [0.87–1.62]

72 (69.2%)

0.85 [0.51–1.42]

   ≥4 times/week

523 (15.5%)

83 (19.2%)

1.50 [1.05–2.15]

13 (12.5%)

0.68 [0.33–1.39]

   

Ptrend = 0.14

 

Ptrend = 0.76

  1. aSubgroups may not total to 3998 because of missing values
  2. b No distal colorectal neoplasia diagnosed at FS
  3. cIncluding 8 cases of screening detected CRC
  4. dAll variables are specified in the Additional file 1
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BMC Gastroenterology

ISSN: 1471-230X

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