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Table 3 Clinical features of TCP and FCPD patients grouped according to their genotype at in/del polymorphism at ACE gene

From: Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis

 

TCP

FCPD

Total

 

II

ID/DD

P value

II

ID/DD

P value

II

ID/DD

P value

n

30

61

-

19

61

-

49

122

-

Sex (Male/Female)

22/8

39/22

-

17/2

42/19

-

39/10

81/41

-

Age at onset (yrs)

25.7 ± 11.1

24.8 ± 11.8

0.72

34.4 ± 15.1

31.2 ± 12.9

0.37

29.0 ± 13.3

28.0 ± 12.7

0.64

Age at presentation (yrs)

36.2 ± 11.8

32.7 ± 10.9

0.16

40.3 ± 17.0

38.9 ± 13.9

0.72

37.8 ± 14.0

35.8 ± 12.9

0.37

Age at onset of diabetes (yrs)

NA

NA

NA

34.2 ± 13.9

33.7 ± 11.44

0.88

34.2 ± 13.9

33.7 ± 11.4

0.81

Pancreatic surgery

11 (36.67%)

24 (40%)

0.76

2 (10.53%)

4 (6.56%)

0.57

13 (26.53%)

28 (23.14%)

0.64

Calcification

30 (100%)

61 (100%)

1

19 (100)

61 (100)

1

49 (100)

122 (100)

1

Pseudocyst

2 (6.67%)

4 (6.6%)

1

0 (0%)

1 (1.64)

1

2 (4.08%)

5 (4.13%)

1

  1. n, number of individuals; TCP, tropical calcific pancreatitis; FCPD, fibro-calculous pancreatic diabetes; ACE, angiotensin converting enzyme
  2. I/D, insertion/deletion polymorphism at ACE locus; NA, not applicable; figures in parentheses indicate percentage; figures are quoted as mean ± SD
  3. P values are represented on comparison of II vs ID+DD genotypes in TCP, FCPD and total patients