Skip to main content

Table 3 Clinical features of TCP and FCPD patients grouped according to their genotype at in/del polymorphism at ACE gene

From: Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis

  TCP FCPD Total
  II ID/DD P value II ID/DD P value II ID/DD P value
n 30 61 - 19 61 - 49 122 -
Sex (Male/Female) 22/8 39/22 - 17/2 42/19 - 39/10 81/41 -
Age at onset (yrs) 25.7 ± 11.1 24.8 ± 11.8 0.72 34.4 ± 15.1 31.2 ± 12.9 0.37 29.0 ± 13.3 28.0 ± 12.7 0.64
Age at presentation (yrs) 36.2 ± 11.8 32.7 ± 10.9 0.16 40.3 ± 17.0 38.9 ± 13.9 0.72 37.8 ± 14.0 35.8 ± 12.9 0.37
Age at onset of diabetes (yrs) NA NA NA 34.2 ± 13.9 33.7 ± 11.44 0.88 34.2 ± 13.9 33.7 ± 11.4 0.81
Pancreatic surgery 11 (36.67%) 24 (40%) 0.76 2 (10.53%) 4 (6.56%) 0.57 13 (26.53%) 28 (23.14%) 0.64
Calcification 30 (100%) 61 (100%) 1 19 (100) 61 (100) 1 49 (100) 122 (100) 1
Pseudocyst 2 (6.67%) 4 (6.6%) 1 0 (0%) 1 (1.64) 1 2 (4.08%) 5 (4.13%) 1
  1. n, number of individuals; TCP, tropical calcific pancreatitis; FCPD, fibro-calculous pancreatic diabetes; ACE, angiotensin converting enzyme
  2. I/D, insertion/deletion polymorphism at ACE locus; NA, not applicable; figures in parentheses indicate percentage; figures are quoted as mean ± SD
  3. P values are represented on comparison of II vs ID+DD genotypes in TCP, FCPD and total patients