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Table 2 Allele frequency and genotype distribution of I/D polymorphism at ACE locus in TCP patients & control subjects

From: Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis

 

Patients

Controls

P Value

 

TCP

FCPD

Total

 

TCP vs. FCPD

TCP vs. controls

FCPD vs. controls

n

91

80

171

99

-

-

-

Allele frequency

       

   I

0.56

0.52

0.54

0.53

0.57

0.67

0.89

   D

0.44

0.48

0.46

0.47

   

Genotype frequency based on the presence or absence of the mutant allele

       

   II

0.33 (30)

0.24 (19)

0.29 (49)

0.26 (26)

0.16

0.28

0.74

   ID + DD

0.67 (61)

0.76 (61)

0.71 (122)

0.74 (73)

   
  1. n, number of individuals; TCP, tropical calcific pancreatitis; FCPD, fibro-calculous pancreatic diabetes; ACE, angiotensin converting enzyme; I/D, insertion/deletion polymorphism at ACE locus figures in parentheses indicate number of individuals; P values are represented on comparison of TCP with FCPD, TCP with controls and FCPD with controls.