Skip to main content

Table 1 patient characteristics:

From: The changes in renal function after a single dose of intravenous furosemide in patients with compensated liver cirrhosis

Characteristics Group 1 Furosemide 40 mg (n = 8) Group 2 Furosemide1 120 mg (n = 10) P value
Age (years) 56.5 ± 9.6 54 ± 9.0 NS
Sex ratio (M/F) 5/3 6/4 NS
Etiology : Alcoholic 3 4 NS
   Non alcoholic 5 6 NS
Serum albumin(g/L) 39 ± 4 40 ± 5 NS
INR 1.09 ± 0.1 1.1 ± 0.1 NS
Bilirubin (micromol/L) 20.5 ± 34.9 18.8 ± 8.5 NS
Child-Pugh's score 5–6 5–6 NS
MELD score 7 8 NS
Serum sodium(mEq/L) 136 ± 1.0 137 ± 1.6 NS
Median (range) 136 (134–138) 136 (133–139)  
Serum creatinine (micromol/L)    
   Base line 77.8 ± 14 81.3 ± 15 NS
   After 1 week follow up 79.6 ± 13 82.2 ± 16.8 NS
Creatinine clearance (ml/min) 82.6 ± 30.4 89.8 ± 32.0 NS
Median (range) 73 (56–142) 92 (41–150)  
8-hours UNa (before, median, range) 87 ± 26 (80, 60–122) 97 ± 32 (107, 37–128) NS
8-hours UNa (After mEq, median, range) 100 ± 36 (96,42–147) 136 ± 37 (127, 92–213) 0.05
% Change +15% +40% 0.01
DMSA Uptake (Nl > 20%)    
   Before Furosemide (median, range) 12.8 ± 3.8 (14, 3–17) 10.6 ± 4.6 (10, 3–21) 0.001
   After Furosemide (median, range) 15.2 ± 2.2 (16, 10–20) 13.5 ± 3.6 (15, 6–21) 0.001
% Change +19% +27%  
  p < 0.001 p = <0.003