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Table 5 Sensitivity, specificity and predictive values of NashTest for the diagnosis of NASH

From: Diagnostic value of biochemical markers (NashTest) for the prediction of non alcoholo steato hepatitis in patients with non-alcoholic fatty liver disease

NashTest diagnosis Histological Diagnosis
  Training Group n = 160 Validation Group n = 97 All patients n = 257
  Se Sp PPV NPV Sensitivity Specificity PPV NPV Sensitivity Specificity PPV NPV
NASH 11/28
39%
122/132
92%
11/21
52%
Prevalence = 0.18
122/139
88%
10/35
29%
61/62
98%
10/11
91%
Prevalence = 0.36
61/86
71%
21/63
33%
183/194
94%
21/32
66%
Prevalence = 0.25
183/225
81%
Borderline or NASH 96/103
93%
20/57
35%
96/133
72% Prevalence = 0.64
20/27
74%
44/56
79%
29/41
71%
44/56
79%
Prevalence = 0.58
29/41
71%
140/159
88%
49/58
50%
140/189
74%
Prevalence = 0.62
49/68
72%