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Table 1 Serum cytokine levels during induction of experimental pancreatitis in R122H-trypsinogen transgenic mice and controls:

From: Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen

   untreated 8 h 24 h 48 h
cytokines (pg/ml)   R122H control R122H control R122H control R122H control
MCP-1 mean ND ND 242,0 279,0 137,0 84,0 75,0 72,0
  SD    137,0 91,0 77,0 26,0 42,0 30,0
Il-6 mean ND ND 60,0 74,0 6,0 9,0 6,0 4,0
  SD    56,0 76,0 3,0 17,0 6,0 3,0
Il-10 mean ND ND 5,0 6,0 3,0 2,0 4,0 2,0
  SD    2,0 5,0 1,0 0,0 4,0 0,0
Il-12p70 mean ND ND 15,0 18,0 7,0 15,0 8,0 20,0
  SD    11,0 13,0 1,0 16,0 5,0 16,0
TNF mean ND ND 10,0 10,0 8,0 5,0 9,0 7,0
  SD    1,0 2,0 1,0 3,0 5,0 3,0
IFN-γ mean ND ND 0,5 0,5 0,5 0,5 0,5 0,5
  SD    0,0 0,0 0,0 0,0 0,0 0,0
  1. Results are expressed as means and standard deviation (n = 10). ND = detectable. There were no significant differences between transgenic animals and controls.