Factors associated with disease evolution in Greek patients with inflammatory bowel disease

BMC Gastroenterology

Table 4 Univariate analysis of overall risk for proximal extension in patients with proctitis at diagnosis

	Patients with disease progression (N = 25)	Patients without disease progression (N = 37)	P ^§
Males	15 (60%)	24 (64.8%)	NS
Urban residence	19 (76%)	21 (56.7%)	0.200^†
Months to diagnosis	21 ± 50.4	27.1 ± 31.7	0.125^†
Age at diagnosis (yr)	43.8 ± 15.4	34.6 ± 13.4	NS
Positive family history	2 (8%)	6 (16.2%)	NS
Current smoking	2 (8%)	14 (37.8%)	0.042
Previous appendectomy	2 (8%)	2 (5.4%)	NS
Chronic continuous course	3 (12%)	1 (2.7%)	0.189^†
Immunosuppressive drugs	0*	1 (2.7%)	NS

Values are given as mean ± SD or number of patients; Values in parentheses are percentages; N, number; *Data collected until change of disease extent; ^§P values from survival analysis using log-rank test; ^†Variables having a p value between 0.51 and 0.2, although insignificant, were included in the regression analysis to avoid confounding effects;

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