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Figure 4 | BMC Gastroenterology

Figure 4

From: Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia

Figure 4

Representative cross sections of extrahepatic bile ducts in IL-12KO mice. Panels A and B show the normal epithelium and unobstructed lumen at 7 and 14 days after the injection of saline in the first 24 hours of life. In contrast, the injection of RRV leads to an obstruction of the lumen by inflammatory cells at day 7, and by sloughed epithelial cells of cellular debris at 14 days (panels C, D). Scale bar: 100 μ.

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