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Table 1 Comparisons of clinical features in patients with chronic hepatitis B treated with IFN alone or IFN plus lamivudine

From: Bone mineral density and cytokine levels during interferon therapy in children with chronic hepatitis B: does interferon therapy prevent from osteoporosis?

Variables IFN-alpha (n = 19) IFN plus Lamivudine (n = 35) P
TNF-α 24.48 ± 8.46 26.60 ± 7.43 NS
IL-1β 7.56 ± 10.86 7.08 ± 12.47 NS
IL-2r 1472.42480.47 1333.72 ± 472.51 NS
IL-6 24.85 ± 31.46 25.57 ± 29.43 NS
IL-8 18.19 ± 13.88 18.73 ± 14.27 NS
PTH 42.03 ± 29.41 40.99 ± 26.92 NS
s-CTX 1.88 ± 0.68 1.96 ± 0.75 NS
Osteocalcin 65.49 ± 34.45 63.85 ± 32.67 NS
Serum calcium 9.28 ± 1.76 9.86 ± 1.69 NS
ALP 249.45 ± 71.34 193.09 ± 72.88 NS
ALT 62.83 ± 76.39 61.45 ± 81.54 NS
AST 59.16 ± 61.48 57.66 ± 59.82 NS
L2–4 BMD 0.63 ± 0.09 0.61 ± 0.14 NS
Femur neck BMD 0.78 ± 0.12 0.82 ± 0.17 NS
Trochanter BMD 0.67 ± 0.16 0.69 ± 0.12 NS