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Table 2 Pre-treatment Variables Influencing HBeAg Loss

From: High rates of early HBeAg seroconversion and relapse in Indian patients of chronic hepatitis B treated with Lamivudine: results of an open labeled trial

Variable HBeAg Loss (n = 35) No HBeAg Loss (n = 25) p value
Age (years) 37.5 44 ns
Sex    
   Male 29 21 ns
   Female 6 4  
Weight (Kg) 60 55 ns
BMI 23.1 22.7 ns
Median ALT (U/L) 94 45 0.002
   Range 32–394 27–254  
Median HBV-DNA (mEq/ml) 111.3 958 0.004
   Range 0.8–4500 4.2–3500  
Cirrhosis    
   Present 13 10 ns
   Absent 22 15  
ALT Normalization    
   Yes 23 5 0.02(df = 1)
   No 9 13