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Table 2 Parameters of the endotoxin dose-response curves for food intake over time. Results of the fitted model examining the effect of various doses of endotoxin on nocturnal food intake extended to include the four nights after LPS injection.

From: A conscious mouse model of gastric ileus using clinically relevant endpoints

Parameter

Estimate

95% Confidence Interval

A – minimum, grams

0.13

(0.05, 0.21)

B – baseline, grams

3.50

(3.61, 3.72)

D m (1) – median effect dose for the first night, mg/kg

0.010

(0.007, 0.012)

c – multiplier of the median effect dose for each additional night

11.00

(8.62, 14.04)

s B – standard deviation of B, g

0.27

(0.18, 0.39)

s D – standard deviation of logD m (1), g

0.47

(0.33, 0.66)

s – residual standard deviation, grams

0.23

(0.20, 0.26)