Induction of post-operative ileus. Twelve hour measurements are plotted as described in legend for Figure 2. Mice were anesthetized, a laparotomy performed, and the cecum manipulated with cotton tipped swabs for 1 minute at time 0 (solid line). Control mice received anesthesia for a similar time (dashed line). N = 10 mice per group. * P = 0.008 vs. control at corresponding time point.