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Table 3 Features of HFE C282Y homozygotes. Cases 1–3 were from Norwich, cases 1 and 2 were included in our previous study [11].

From: Hepatocellular carcinoma and the penetrance of HFEC282Y mutations: a cross sectional study

  Histology (and histological staging of fibrosis) Grade of Siderosis (liver iron) Venesectiona Age# Sex
1 HCC (inadequate for staging) NA* No 66 M
2 HCC, cirrhosis (inadequate for staging) Grade 1 No 70 M
3 HCC (inadequate for staging) Grade 3/4 Yes 64 M
4 HCC, fibrosis (stage 4) Grade 2/3 Yes 64 M
5 HCC, cirrhosis (stage 6) Grade 4 No 73 M
6 HCC, fibrosis (stage 4) Grade 1 Yes 64 M
7 HCC, cirrhosis (stage 6) Grade 4 Not known 63 M
8 HCC, cirrhosis (stage 6) Grade 2/3 Yes 62 M
  1. a Information about previous venesection treatment obtained from histology request forms and reports.
  2. # Age at biopsy.
  3. * Not applicable; only tumour was present in the needle biopsy sample.
  4. HCC, hepatocellular carcinoma.