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Table 2 HFE genotypes for codon 282 of HCC cases and control cohorts. Ages in years and numbers (percentages) of cases with each genotype.

From: Hepatocellular carcinoma and the penetrance of HFEC282Y mutations: a cross sectional study

  HCC Patients Controls *  
Mean Age 54 a 57  
CC (normal) 119 (82.6%) 1331 (88.2%)  
CY (heterozygotes) 17 (11.8%) 168 (11.1%) p = 0.34
YY (homozygotes) 8 (5.6%) 9 (0.6%) p = 0.00003
Total Number 144 1508  
  1. p values are single tailed probabilities of over-representation of mutant genotypes in HCC patients by Fisher's exact test.
  2. * Norfolk data presented in Willis et al. 2002 [12], Cambridge data presented in Halsall et.al. 2003 [14].
  3. a age data available for only 138/144 cases.
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BMC Gastroenterology

ISSN: 1471-230X

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