Figure 4

Effects of EGF and HRG-α on invasion through Matrigel in Capan-1 and MIA PaCa-2 cells. Cells were cultured on invasion chambers coated with Matrigel, and invasion measured following treatment with no growth factor, 10 nM EGF, or 10 nM HRG-α. Shown are the results of 3 experiments, each performed in triplicate wells. *p < 0.05 between the no growth factor group and the EGF treatment group for each cell type.