Table 3 Correlation between amino acid concentrations and fatigue for patients with PBC
| VAS | FFSS, physical domain | FFSS, cognitive domain | FFSS, social domain | ||
|---|---|---|---|---|---|
| Aromatic amino acids | Tyrosine |
-0.38 p = 0.01 |
-0.37 p = 0.01 |
-0.40 p = 0.006 |
-0.37 p = 0.01 |
| Phenylalanine |
-0.27 p = 0.08 |
-0.29 p = 0.05 |
-0.25 p = 0.10 |
-0.31 p = 0.04 | |
| Tryptophan |
-0.25 p = 0.10 |
-0.36 p = 0.02 |
-0.42 p = 0.004 |
-0.33 p = 0.03 | |
| Branched chain amino acids | Valine |
-0.10 p = 0.50 |
-0.21 p = 0.16 |
-0.06 p = 0.70 |
-0.04 p = 0.79 |
| Isoleucine |
-0.04 p = 0.76 |
-0.09 p = 0.54 |
0.06 p = 0.70 |
0.09 p = 0.58 | |
| Leucine |
-0.09 p = 0.57 |
-0.16 p = 0.29 |
0.01 p = 0.98 |
0.02 p = 0.89 | |
| Calculated ratio's | Tryptophan-ratio |
-0.02 p = 0.87 |
-0.07 p = 0.66 |
-0.26 p = 0.09 |
-0.19 p = 0.22 |
| Tyrosine-ratio |
-0.30 p = 0.048 |
-0.21 p = 0.15 |
-0.34 p = 0.02 |
-0.32 p = 0.03 |