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Figure 2 | BMC Gastroenterology

Figure 2

From: TGF β1 and PDGF AA override Collagen type I inhibition of proliferation in human liver connective tissue cells

Figure 2

Collagen-mediated inhibition of proliferation. A. Cell proliferation of LCTC plated on increasing collagen concentration as measured by [H3]-Thymidine incorporation (n = 4). Note inhibition of incorporation in a dose-dependent manner. B. Cell proliferation of SF plated on increasing collagen concentration as measured by [H3]-Thymidine incorporation (n = 4). Note inhibition of incorporation in a dose-dependent manner. (*) denotes significant difference from control; p0.05. C. Left panel. Kinetics of DNA synthesis of LCTC comparing growth on plastic (empty circles) and on collagen (filled circles) (n = 4). Right panel, top. Adhesion of cells plated on plastic (filled circles), collagen IV (empty triangles) and collagen I (empty squares) (n = 3). Right panel, bottom. Recovery of cells from plastic or collagen I (n = 4).

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