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Table 1 Group definitions and demographics of the cases studied.

From: Colon biopsies for evaluation of acute graft-versus-host disease (A-GVHD) in allogeneic bone marrow transplant patients

  Group A Group B Group C
  Positive group with A-GVHD by skin biopsy*.
Cases of BMT. Underlying indications for BMT are shown as the foot notes of this table**.
With diarrhea and without identifiable infectious etiology and history of drugs like NSAIDs, steroids.
Negative control group I.
Without any transplantation and immunosupresion.
With GI symptoms like diarrhea, guaiac positive stool.
Negative control group II.
With kidney transplantation***.
With GI symptoms like diarrhea, guaiac positive stool.
Age    
   Mean 41.6 years 51.5 years 60.3 years
SD 9.2 12.5 8
Range 19 to 59 years 20 to 77 years 46 to 75 years
Sex    
   Males 25 13 14
Females 19 14 7
Total 44* 27 21
  1. *The splitting of total cases according to the grading of cutaneous A-GVHD: Grade I- 20, Grade II- 13, Grade III- 5, Grade IV- 6. **The diagnoses for which BMT was done includes: Hodgkin's Lymphoma (3), Non-Hodgkin's Lymphoma (4), T-cell Lymphoblastic Lymphoma (5), IgG Multiple myeloma (3), Plasma cell leukemia (1), Chronic Myelogenous Leukemia (17), Chronic myelomonocytic Leukemia (2), Myelodysplastic syndrome (1), and Others (8). All cases received the same conditioning regimen (cyclophosphamide [Cytoxan], cytosine arabinoside, and total body irradiation). The type of A-GVHD prophylaxis used was post-transplatation cyclosporin A. ***The duration of kidney transplantation ranged from 8 to 64 months (mean 28 months).