Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? A meta analysis of randomized clinical trials

Table 1 Description of gastric ulcer studies by drug, sample size and dosage. Ital Coop Grp: Italian Cooperative Group, Coop St Group: Cooperative Study Group.

Author	Study Drug	Dose (mg/d)	N	Comparator	Dose (mg/d)	N
Florent [24]	Lansoprazole	30	60	Omeprazole	20	66
Witzel [25]	Pantoprazole	40	163	Omeprazole	20	80
Dekkers [26]	Rabeprazole	20	113	Omeprazole	20	114
Avner [12]	Lansoprazole	15	68	Placebo		67
		30	67
		60	63
Valenzuela [13]	Omeprazole	20 40	202 214	Placebo		104
Cloud [14]	Rabeprazole	20 40	32 31	Placebo		31
Humphries [27]	Rabeprazole	20 40	32 31	Placebo		31
Bardhan [15]	Lansoprazole	30 60	82 85	Ranitidine	300	83
Michel [16]	Lansoprazole	30	79	Ranitidine	300	79
Classen [17]	Omeprazole	20	83	Ranitidine	300	74
Coop St Group [18]	Omeprazole	40	21	Ranitidine	300	25
Ital Coop Grp [19]	Omeprazole	20	84	Ranitidine	300	83
Walan [20]	Omeprazole	20 40	203 194	Ranitidine	300	205
Choi [21]	Omeprazole	20	125	Ranitidine	300	125
Bader [22]	Pantoprazole	40	192	Ranitidine	300	123
Hotz [23]	Pantoprazole	40	166	Ranitidine	300	82

ISSN: 1471-230X