Figure 1
From: Cathepsin B cleavage of the trypsinogen activation peptide
pH dependent hydrolysis of synthetic peptides by cathepsin B. Wild type and mutant (pD22G, pK23R) peptides were incubated with or without cathepsin B for 30 minutes. After chromatographic separation of the hydrolytic products, the percentage of peptide digestion was measured by integration of the areas under the respective peaks.