Effects of glucose on the expression of apoptosis related factors in vitro. (A) Effects of glucose on the protein expression of AKT, ERK, Bax and Bcl-2 in DCs treated with LPS for different periods of time. At high glucose concentrations at 24 h LPS stimulation, the protein expression of AKT, ERK and Bcl-2 decreased, while BAX increased. These effects were not evident in cells treated with LPS for 15 min and 6 h. Actin is internal control. Figure 5.B is the statistical chart. Gray values of target bands were divided by Actin to obtain normalized data. #p < 0.05 vs. control mice.