From: Acid suppressive agents and risk of Mycobacterium Tuberculosis: case–control study
Characteristics | Case n = 6541 (%) | Control n = 65410 (%) | OR (95%CI) |
---|---|---|---|
Age (mean ± SD) | 57.78(±19.55) | ||
Sex Male/Female | 4277/2264 | 42770/22640 | 1.0000 |
Income category | |||
Monthly income ≦ NT$20000 | 5371(82.11) | 52016(79.52) | 0.79-0.90 |
Monthly income > NT$20000 | 1170(17.89) | 13394(20.48) | |
Comorbidity | |||
Congestive heart failure | 304(4.65) | 1224(1.87) | 2.56(2.25-2.91) |
Coronary heart disease | 727(11.11) | 5674(8.67) | 1.32(1.21-1.43) |
Chronic pulmonary disease | 1087(16.62) | 2524(3.86) | 4.97(4.60-5.36) |
Diabetes mellitus | 1274(19.48) | 6234(9.53) | 2.30(2.14-2.45) |
End stage renal disease | 182(2.82) | 799(1.22) | 2.32(1.97-2.73) |
Liver cirrhosis | 696(10.64) | 3952(6.04) | 1.85(1.70-2.02) |
Alcohol abuse | 91(1.39) | 229(0.35) | 4.02(2.15-5.13) |
Peptic ulcer disease | 1106(16.90) | 6823(10.43) | 1.75(1.63-1.87) |
Reflux esophagitis | 103(1.57) | 664(1.02) | 1.56(1.27-1.92) |
Gastrectomy | 23(0.35) | 149(0.23) | 1.55(1.01-2.40) |
HIV | 12 (0.18) | 3(0.00) | 40.04(11.3-141.9) |
Connective tissue disease | 245(3.75) | 1357(2.07) | 1.84(1.60-2.11) |
Malignant neoplasm | 704(10.76) | 1906(2.91) | 4.02(3.67-4.40) |
Organ transplantation | 21(0.32) | 58(0.08) | 3.63(2.20-5.99) |
Medication | |||
PPI | 173(2.64) | 723(1.11) | 2.43(2.06-2.88) |
H2RA | 338(5.16) | 1828(2.79) | 1.90(1.68-2.14) |