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Table 2 Characteristics of cases with TB infection/activation and control subjects

From: Acid suppressive agents and risk of Mycobacterium Tuberculosis: case–control study

Characteristics

Case n = 6541 (%)

Control n = 65410 (%)

OR (95%CI)

Age (mean ± SD)

57.78(±19.55)

Sex Male/Female

4277/2264

42770/22640

1.0000

Income category

   

Monthly income NT$20000

5371(82.11)

52016(79.52)

0.79-0.90

Monthly income > NT$20000

1170(17.89)

13394(20.48)

 

Comorbidity

   

Congestive heart failure

304(4.65)

1224(1.87)

2.56(2.25-2.91)

Coronary heart disease

727(11.11)

5674(8.67)

1.32(1.21-1.43)

Chronic pulmonary disease

1087(16.62)

2524(3.86)

4.97(4.60-5.36)

Diabetes mellitus

1274(19.48)

6234(9.53)

2.30(2.14-2.45)

End stage renal disease

182(2.82)

799(1.22)

2.32(1.97-2.73)

Liver cirrhosis

696(10.64)

3952(6.04)

1.85(1.70-2.02)

Alcohol abuse

91(1.39)

229(0.35)

4.02(2.15-5.13)

Peptic ulcer disease

1106(16.90)

6823(10.43)

1.75(1.63-1.87)

Reflux esophagitis

103(1.57)

664(1.02)

1.56(1.27-1.92)

Gastrectomy

23(0.35)

149(0.23)

1.55(1.01-2.40)

HIV

12 (0.18)

3(0.00)

40.04(11.3-141.9)

Connective tissue disease

245(3.75)

1357(2.07)

1.84(1.60-2.11)

Malignant neoplasm

704(10.76)

1906(2.91)

4.02(3.67-4.40)

Organ transplantation

21(0.32)

58(0.08)

3.63(2.20-5.99)

Medication

   

PPI

173(2.64)

723(1.11)

2.43(2.06-2.88)

H2RA

338(5.16)

1828(2.79)

1.90(1.68-2.14)

  1. Abbreviations: TB, Mycobacterium Tuberculosis; CI, confidence interval; SD, standard deviation; NT, New Taiwan dollars; OR, odds ratio; HIV, human immunodeficiency virus; PPI, proton pump inhibitor; H2RA, histamine2-receptor antagonist.