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Table 5 Scores of liver from chow diet, FFD and FFD-CCl 4

From: Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model

Histological scores Chow diet control 0.5 ml/Kg B.wt CCl4 FFD FFD + 0.5 ml/kg B.wt CCl4
Fibrosis 00 ± 00 00 ± 00 0.92 ± 0.12*** 2.30 ± 0.21***
Steatosis – micro vesicular 0.33 ± 0.14 0.75 ± 0.13 2.00 ± 0.21*** 2.60 ± 0.16***
Steatosis – macro vesicular 00 ± 00 00 ± 00 1.92 ± 0.19*** 2.50 ± 0.17***
Hepatocellular ballooning 00 ± 00 0.25 ± 0.13 1.00 ± 0.17*** 1.50 ± 0.17***
Inflammation 0.75 ± 0.22 1.00 ± 0.25 1.75 ± 0.22** 2.00 ± 0.26**
  1. All data are expressed as mean ± SEM. The data was statistically analyzed for significant using one-way ANOVA followed by Dunnett’s multiple comparison post test, **p < 0.01 and ***p < 0.001.