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Table 5 Scores of liver from chow diet, FFD and FFD-CCl 4

From: Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model

Histological scores

Chow diet control

0.5 ml/Kg B.wt CCl4

FFD

FFD + 0.5 ml/kg B.wt CCl4

Fibrosis

00 ± 00

00 ± 00

0.92 ± 0.12***

2.30 ± 0.21***

Steatosis – micro vesicular

0.33 ± 0.14

0.75 ± 0.13

2.00 ± 0.21***

2.60 ± 0.16***

Steatosis – macro vesicular

00 ± 00

00 ± 00

1.92 ± 0.19***

2.50 ± 0.17***

Hepatocellular ballooning

00 ± 00

0.25 ± 0.13

1.00 ± 0.17***

1.50 ± 0.17***

Inflammation

0.75 ± 0.22

1.00 ± 0.25

1.75 ± 0.22**

2.00 ± 0.26**

  1. All data are expressed as mean ± SEM. The data was statistically analyzed for significant using one-way ANOVA followed by Dunnett’s multiple comparison post test, **p < 0.01 and ***p < 0.001.