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Table 3 Serum biochemical profile

From: Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model

Parameters

Chow diet control

0.5 ml/Kg B.wt CCl4

FFD only

FFD + 0.5 ml/kg B.wt CCl4

AST (IU/L)

118.0 ± 6.93

126.3 ± 2.85

138.4 ± 6.91*

146.7 ± 6.91**

ALT (IU/L)

54.92 ± 1.25

59.17 ± 0.95

62.73 ± 7.72

69.60 ± 4.15*

ALP (IU/L)

87.67 ± 6.86

102.4 ± 7.44

228.8 ± 38.44***

227.8 ± 31.62***

GGT (IUL)

0.09 ± 0.04

0.06 ± 0.06

0.00 ± 0.00

3.30 ± 1.17***

Procollagen type III (ng/ml)

5.61 ± 0.61

5.65 ± 0.65

8.29 ± 0.58

14.96 ± 2.19***

Triglycerides (mg/dL)

145.3 ± 14.28

96.72 ± 8.54*

77.17 ± 7.90**

75.43 ± 4.30**

  1. Effect on serum clinical chemistry markers; data are expressed as mean ± SEM. Statistical significance was determined using one-way ANOVA followed by Dunnett’s multiple comparison post test, *p < 0.05, **p < 0.01 and ***p < 0.001.