Table 3 Clinical and biochemical characteristics in subjects without diabetes, or obesity or metabolic syndrome and in statin non users according to the presence or absence of NAFLD
Subjects w/o diabetes | Subjects w/o obesity^ | Subjects w/o MetS | Subjects w/o statin use | |||||
|---|---|---|---|---|---|---|---|---|
Nafld (144) | no-Nafld (43) | Nafld (85) | no-Nafld (39) | Nafld (73) | no-Nafld (41) | Nafld (139) | no-Nafld (28) | |
Age (yrs) | 52,1 ± 12,7 | 54,4 ± 14 | 55,0 ± 13,0 | 55,0 ± 14,7 | 50,1 ± 13,1 | 54,7 ± 13,0 | 50,8 ± 11,8 | 53,0 ± 15,9 |
Male gender (%) | 33,3 | 34,9 | 23,8 | 34,2 | 31,8 | 30,6 | 36,0 | 39,3 |
BMI | 30,9 ± 5,6 | 26,9 ± 3,7 *** | 26,6 ± 2,3 | 25,2 ± 2,0*** | 29,5 ± 5,7 | 26,5 ± 3,5** | 31,0 ± 5,8 | 27,2 ± 3,9*** |
Urinary 8-iso-PGF2α (pg/mg creatinine) | 703,4 ± 117,9 | 634,1 ± 106,7*** | 626,6 ± 81,5 | 583,6 ± 102,7* | 672,1 ± 123,0 | 619,3 ± 95,1* | 711,6 ± 133 | 627,5 ± 147,9** |
sNOX2-dp (pg/ml) | 56,4 ± 13,8 | 49,9 ± 8,9*** | 49,4 ± 12,9 | 45,8 ± 8,9 | 54,0 ± 13,3 | 48,4 ± 8,3* | 57,5 ± 14,1 | 47,5 ± 10,7*** |
Adiponectin (ng/ml) | 8,5 (5,5/12) | 13,5 (7,5/15)*** | 12,5 (10,5/14) | 13,5 (12,5/14,5)** | 10,5 (6,2/13,6) | 13,0 (6,5/14)* | 7,5 (5/11,5) | 13,5 (6,8/15)*** |
Cytokeratin-18 (mIU/ml) | 174,5 (136/189) | 130,0 (125/175)** | 149,0 (125/179) | 126,0 (110/165)* | 161,5 (125/180 | 165,0 (125/178) | 179,0 (145/190) | 140,0 (125/179)** |
ALT (IU/L) | 26 (20/40) | 20 (15/27)*** | 34 (23/42) | 15 (13/24)*** | 26 (19/27) | 18 (14/27)** | 27 (20/40) | 18 (14/27)*** |
GGT (IU/L) | 25 (17/40)* | 20 (14/28) | 30 (20/52) | 21 (16/23)** | 23 (16/10) | 21 (18/36) | 25 (17/44)* | 21 (13/30) |
HOMA_IR | 2,9 (2,1/4,5) | 1,8 (1,2/2,1)*** | 2,8 (1,8/4,3) | 2,0 (1,6/3,2) | 2,6 (1,7/3,4) | 1,8 (1,5/2,1)* | 3,1 (2,2/5,5) | 1,8 (1,1/2,1)*** |
MetS§ (%) | 57,0 | 12,5*** | 51,8 | 19,4*** | 0 | 0 | 57,8 | 16,0*** |
High Fasting Glucose§ (%) | 32,9 | 19,5 | 44,0 | 30,6 | 15,2 | 13,9 | 41,3 | 23,1 |
High Triglycerides§ (%) | 44,8 | 11,9*** | 39,3 | 16,2* | 7,6 | 13,9 | 40,9 | 11,1** |
High Waist Circumference§ (%) | 78,2 | 43,9*** | 55,4 | 27,0** | 59,1 | 38,9 | 80 | 46,2*** |
Low C-HDL§ (%) | 35,7 | 16,7* | 31,0 | 21,6 | 6,1 | 13,9 | 37,2 | 14,8* |
High Blood Pressure§ (%) | 79,0 | 74,4 | 81,0 | 73,7 | 69,7 | 75,0 | 80,3 | 75,0 |
Diabetes (%) | 0 | 0 | 21,4 | 15,8 | 7,6 | 2,8 | 20,1 | 7,1 |
Statin use (%) | 22,9 | 39,5* | 31,0 | 47,4 | 13,6 | 41,7** | 0 | 0 |