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Table 1 Clinical and biochemical characteristics of subjects with and without NAFLD

From: NOX2-generated oxidative stress is associated with severity of ultrasound liver steatosis in patients with non-alcoholic fatty liver disease

  NAFLD (213) w/o NAFLD (51) p
Age (yrs) 54,3 ± 12 56,1 ± 14,4 Ns
Male Gender (%) 64,6 63,3 Ns
BMI (kg/m2) 31,6 ± 5,6 26,8 ± 3,6 <0,001
Urinary 8-iso-PGF2α (pg/mg creatinine) 714,4 ± 121,5 621,2 ± 125,9 <0,001
sNOX2-dp (pg/ml) 57,4 ± 13.6 47,8 ± 9.9 <0.001
Adiponectin (ng/ml) 8,5 (5/12) 13 (8/15) <0,001
Cytokeratin 18 (mIU/ml) 180 (146/190) 136 (125/173) <0,001
ALT (IU/L) 27,5 (20/40) 18 (14/27) <0,001
HOMA_IR 3,5 (2,4/5,9) 1,9 (1,3/2,3) <0,001
Metabolic syndrome (%)* 67,7 21,7 <0,001
High fasting glucose (%)* 53,8 29,8 < 0,01
Hypertriglyceridemia (%)* 46,9 14,6 <0,001
High waist circumference (%)* 81,9 42,6 <0,001
Low HDL-cholesterol (%)* 37,2 18,8 < 0,05
High blood pressure (%)* 84,5 75,5 Ns
Diabetes (%) 31,1 12,2 < 0,01
Statin use (%) 33,5 42,9 Ns
  1. *According to ATPIII modified criteria (Ref. 30).