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Table 7 Summary of predictive potential of biomarkers CD163, TSP-1 and IL-6

From: Biomarkers can predict potential clinical responders to DIMS0150 a toll-like receptor 9 agonist in ulcerative colitis patients

 

Correct prediction

Sensitivity

Specificity

PPV

NPV

Steroid response

81% (17/21)

80%

82%

80%

82%

Enhancing

81% (17/21)

80%

82%

80%

82%

Steroid response and enhancing

90.5% (19/21)

90%

91%

90%

91%

  1. (PPV) Positive predictive value.
  2. (NPV) Negative predictive value.