Figure 1

Cytokine production by human PBMCs stimulated with DIMS0150. Human PBMC from healthy volunteers (n = 5) were stimulated with 0.5 μM or 10 μM of DIMS0150 for 48 hrs. Cell culture supernatants were collected and analysed using CBA flex (IFN-γ, IL-6, IL-10, IP-10, and TNF-α) and ELISA (IFN-α and IFN-β). As control, cytokine levels obtained from PBMC incubated with medium alone were subtracted from all the values. Protein levels [pg/ml] are presented as mean values and SEM bars.