Controls N = 12 | Degree of expression* N = 57 | |||
---|---|---|---|---|
Controls N = 12 | UC = Mild N = 24 | UC = Moderate N = 27 | UC = Severe N = 6 | |
HSP70 constitutive | ||||
Surface epithelium | ||||
Nucleus | ++ (9/12) | ++ (13/24) | ++ (16/27) | ++ (3/6) |
+ (1/12) | + (2/24) | + (5/27) | + (1/6) | |
0– + (1/12) | 0 - + (6/24) | 0 - + (5/27) | 0 - + (2/6) | |
0 (3/24) | 0 (1/27) | |||
Cytoplasm | ++ (8/12) | ++ (7/24) | ++ (5/27) | ++ (3/6) |
+ (2/12) | + (7/24) | + (12/27) | + (0/6) | |
0– + (2/12) | 0 - + (6/24) | 0 - + (8/27) | 0 - + (2/6) | |
0 (4/24) | 0 (2/27) | 0 (1/6) | ||
Crypts | ||||
Nucleus | ++ (7/12) | ++ (2/24) | ++ (13/27) | ++ (3/6) |
+ (2/12) | + (9/24) | + (5/27) | + (1/6) | |
0– + (3/12) | 0 - + (9/24) | 0 - + (8/27) | 0 - + (2/6) | |
0 (4/24) | 0 (1/27) | |||
Cytoplasm | ++ (7/12) | ++ (3/24) | ++ (6/27) | ++ (3/6) |
0– + (4/12) | + (8/24) | + (11/27) | + (0/6) | |
0 (1/12) | 0 - + (9/24) | 0 - + (7/27) | 0 - + (1/6) | |
0 (4/24) | 0 (3/27) | 0 (2/6) | ||
Lamina propria | ||||
Mononuclear cells | + (6/12) | + (14/24) | + (18/27) | + (5/6) |
0 (6/12) | 0 (10/24) | 0 (9/27) | 0 (1/6) | |
Polymorphonuclear cells | 0 (12/12) | + (7/24) | +(16/27) | + (4/6) |
0 (17/24) | 0 (11/27) | 0 (2/6) | ||
HSP70 inducible | ||||
Surface epithelium | ||||
Nucleus | 0– + (2/12) | 0 - + (4/24) | 0 - +(4/27) | ——————— |
0 (10/12) | 0 (20/24) | 0 (23/27) | 0 (6/6) | |
Cytoplasm | 0– + (4/12) | 0 - + (5/24) | 0 - +(6/27) | 0 - + (2/6) |
0 (8/12) | 0 (19/24) | 0 (21/27) | 0 (4/6) | |
Crypts | ||||
Nucleus | 0– + (2/12) | 0 - + (2/24) | 0 - + (2/27) | ———————- |
0 (10/12)) | 0 (22/24) | 0 (25/27) | 0 (6/6) | |
Cytoplasm | 0– + (2/12) | ——————— | 0 - +(1/27) | ——————— |
0 (10/12) | 0 (24/24) | 0 (26/27) | 0 (6/6) | |
Lamina propria | ||||
Mononuclear cells | + (1/12) | + (1/24) | + (1/27) | ——————— |
0 (11/12) | 0 (23/24) | 0 (26/27) | 0 (6/6) | |
Polymorphonuclear cells | 0 (12/12) | + (16/24) | + (21/27) | + (5/6) |
0 (8/24) | 0 (6/27) | 0 (1/6) |