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Table 1 The baseline characteristics and HP infection status, serum PG test of gastric cancer and controls

From: Serum trefoil factor 3 is a promising non-invasive biomarker for gastric cancer screening: A monocentric cohort study in China

 

Gastric cancer (n = 72)

CAG (n = 61)

CNAG (n = 27)

Healthy control (n = 37)

Age(years, mean ± SD)

61.7±1.4ζ

56.7±1.4

48.1±2.8

56.7±2.8

Male/Female ratio

1.23

0.91

0.5

1.31

Histological type

    

  Intestinal type

25(34.7%)

   

  Diffuse type

47(65.3%)

   

TNM stage

    

  Early gastric cancer

16(22.2%)

   

  Advanced gastric cancer

56(77.8%)

   

HP infection status

    

  HP positive

48(66.7%)

30(49.2%)

14(51.8%)

18(48%)

PG test

    

  PG I (ng/ml)

76.91±4.78*

72.02±5.48

79.64±5.74

84.52±4.44

  PG II (ng/ml)

25.10±2.35**

19.44±1.27

18.27±1.93

14.39±1.12

  PG I/II ratio

3.91±0.29ξ

3.99±0.24

5.84±0.72

7.18±0.69

  1. ζ: No difference between gastric cancer and healthy group (P = 0.08); gastric cancer vs CAG P = 0.0179; gastric cancer vs CNAG, P < 0.001.
  2. *: No difference between cancer group and CAG, CNAG and healthy group.
  3. **: Gastric cancer vs. CAG, P = 0.0459; gastric cancer vs. CNAG, P = 0.0927; Gastric cancer vs. healthy, P = 0.002.
  4. ξ: Gastric cancer vs. CAG, P = 0.8485; gastric cancer vs. CNAG, P = 0.0038; gastric cancer vs. healthy, P < 0.0001.