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Table 2 List of obesity related genes significantly upregulated in gastric tissues of patients with the following pathological conditions

From: Expression of energy metabolism related genes in the gastric tissue of obese individuals with non-alcoholic fatty liver disease

Genes Fold regulation P value
Advanced steatosis (grade ≥ 3) vs mild/no steatosis (score < 3)
CPE −1.8 0.04
IL1B −2.5 0.05
NASH present vs No NASH
IL1R1 1.99 0.04
OPRM1 2.65 0.02
SIGMAR1 3.13 0.03
THRB 1.94 0.02
ZFP91 3.09 0.01
Advanced hepatic inflammation (score ≥ 3) vs mild/no hepatic inflammation (score < 3)
ADCYAP1 5.5 0.04
ADRA2B 2.1 0.02
BDNF 3.5 0.03
CNR1 5.1 0.001
CNTFR 3.2 0.02
GALR1 2.5 0.04
GH2 5.1 0.01
GRPR 4.1 0.004
IAPP 2.5 0.03
LEP 2.3 0.04
LEPR 2.3 0.02
MC3R 4.1 0.02
NMB 2.4 0.04
NMU 3.9 0.004
NMUR1 6.9 0.03
PPARGC1A 4.1 0.006
PRLHR 4.2 0.02
RAMP3 2.5 0.02
SIGMAR1 2.3 0.01
SSTR2 3.2 0.04
UCN 4.9 0.04
Fibrosis present vs no fibrosis
NTS 6.7 0.02
OPRK1 5.6 0.01
Gastritis present vs no gastritis
C3 −2.1 0.04
DRD1 2.6 0.02
  1. Advanced Liver Inflammation (score ≥ 3) (N = 13), Advanced Steatosis (score ≥ 3) (N = 10), NASHǂ (N = 15), Fibrosisǂ (N = 19), Gastritisǂ (N = 11). ǂComparison was performed to groups of patients without the condition listed.