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Table 2 List of obesity related genes significantly upregulated in gastric tissues of patients with the following pathological conditions

From: Expression of energy metabolism related genes in the gastric tissue of obese individuals with non-alcoholic fatty liver disease

Genes

Fold regulation

P value

Advanced steatosis (grade ≥ 3) vs mild/no steatosis (score < 3)

CPE

−1.8

0.04

IL1B

−2.5

0.05

NASH present vs No NASH

IL1R1

1.99

0.04

OPRM1

2.65

0.02

SIGMAR1

3.13

0.03

THRB

1.94

0.02

ZFP91

3.09

0.01

Advanced hepatic inflammation (score ≥ 3) vs mild/no hepatic inflammation (score < 3)

ADCYAP1

5.5

0.04

ADRA2B

2.1

0.02

BDNF

3.5

0.03

CNR1

5.1

0.001

CNTFR

3.2

0.02

GALR1

2.5

0.04

GH2

5.1

0.01

GRPR

4.1

0.004

IAPP

2.5

0.03

LEP

2.3

0.04

LEPR

2.3

0.02

MC3R

4.1

0.02

NMB

2.4

0.04

NMU

3.9

0.004

NMUR1

6.9

0.03

PPARGC1A

4.1

0.006

PRLHR

4.2

0.02

RAMP3

2.5

0.02

SIGMAR1

2.3

0.01

SSTR2

3.2

0.04

UCN

4.9

0.04

Fibrosis present vs no fibrosis

NTS

6.7

0.02

OPRK1

5.6

0.01

Gastritis present vs no gastritis

C3

−2.1

0.04

DRD1

2.6

0.02

  1. Advanced Liver Inflammation (score ≥ 3) (N = 13), Advanced Steatosis (score ≥ 3) (N = 10), NASHǂ (N = 15), Fibrosisǂ (N = 19), Gastritisǂ (N = 11). ǂComparison was performed to groups of patients without the condition listed.