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Table 2 Demographic and ECG data in patients with liver cirrhosis at pre-transplant evaluation (with an available ECG) and healthy controls

From: Prevalence of pre-transplant electrocardiographic abnormalities and post-transplant cardiac events in patients with liver cirrhosis

  Cirrhotic patients (n = 186) Controls (n = 92) p-value
Age 52 (11) 51 (11) 0.4
Male sex 134 (71.5%) 61 (62%) 0.104
Current or past smoker 1 92/173 (53%) 30/59 (51%) 0.699
Arterial blood pressure    
 Systolic (mmHg) 119 (17.5) 126 (19.5) 0.004
 Diastolic (mmHg) 68 (11) 77 (11.5) <0.001
Fasting plasma glucose (mmol/L) 6.7 (3.5) 5.0 (0.8) <0.001
Body mass index (kg/m 2 ) 25.4 (4.5) 25.5 (3.5) 0.88
QTc time (sec) 2 0.429 (0.032) 0.406 (0.037) <0.001
 Prolonged QT interval 57 (31.5%) 8 (8%) <0.001
Q wave 23 (12%) 1 (1%) 0.001
Abnormal QRS axis devation 39 (21%) 10 (10%) 0.022
 Left axis deviation (−30° - -90°) 33 (18%) 7 (7%) 0.015
 Right axis deviation (+120° - -150°) 2 (1%) 0 (0%) 0.304
 Indeterminate axis QRS axis approximately +90° from the frontal plane 1 (0.5%) 2 (2%) 0.237
High R waves 17 (9%) 5 (5%) 0.226
ST segment depression 10 (5%) 0 (0%) 0.019
Pathologic T wave 19 (10%) 4 (4%) 0.072
AV conduction defect 13 (7%) 3 (3%) 0.172
 AV- Block 1 10 (5%) 3 (3%) 0.375
 Short PR interval 2 (1%) 0 (0%) 0.303
 High grade AV block 1 (0.5%) 0 (0%) 0.467
Ventricular conduction defect 18 (10%) 10 (10%) 0.887
 Right bundle branch block 2 (1%) 0 (0%) 0.304
 Incomplete right bundle branch block 6 (3%) 1 (1%) 0.257
 Intraventricular block 1 (0.5%) 0 (0%) 0.468
 R-R’ pattern in either of leads V1, V2 with R’ amplitude ≥ R 3 (1.5%) 7 (7%) 0.016
 Incomplete left bundle branch block or RR’ 6 (3%) 2 (2%) 0.571
Arrhythmia 13 (7%) 8 (8%) 0.719
 Presence of frequent atrial or junctional premature beats (≥10% of recorded complexes) 1 (0.5%) 0 (0%) 0.467
Atrial flutter or fibrillation 4 (2%) 0 (0%) 0.144
 Sinus tachycardia (heart rate > 100/min) 3 (1.5%) 0 (0%) 0.206
 Sinus Bradycardia (heart rate < 50/min) 4 (2%) 8 (8%) 0.017
 Other arrhythmias 1 (0.5%) 0 (0%) 0.467
Any miscellaneous criteria 61 (33%) 71 (72%) <0.001
 QRS transition zone to the right of lead V3 16 (9%) 0 (0%) 0.003
 QRS transition zone to the left of lead V3 43 (23%) 71 (72%) <0.001
ECG feature compatible with CAD 3 40 (17%) 5 (5%) <0.001
  1. Data is expressed as n (%) or as mean (SD) as appropriate.
  2. AV; Atrioventricular, CAD; Coronary artery disease.
  3. 1Data were not available in all patients and controls.
  4. 2The QT interval was corrected according to the Bazett formula (16).
  5. 3Q wave, T wave inversion and/or ST-depression (17, 18).