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Table 2 Summary of key papers in patients given MEN for maintenance of remission

From: A retrospective study showing maintenance treatment options for paediatric CD in the first year following diagnosis after induction of remission with EEN: supplemental enteral nutrition is better than nothing!

Paper

Total sample size

Number continued MEN

Route of supplementation

Type of supplementation

Volume taken

Remission rates at 1 year

Verma et al. [21]

33

33

Oral

19 elemental

35-50% EAR

8/19 elemental

Adult population

   

14 polymeric

 

6/14 polymeric

Tageki et al. [22]

51

26

Oral/NG

Elemental

900-1200 ml/calories daily

9/29 elemental*

Adult population

      

Wilschanski et al. [11]

47

28

NGT

elemental or semi-elemental feeds

50-60% EAR for 4 or 5 nights per week overnight

17/28 (p < 0.02)

Paediatric population

      

Knight et al. [26]

40

22

Oral

Elemental or polymeric

1 litre daily

9/22 (not statistically sig)

Paediatric population

      

Day et al. [27]

27

4

Oral

polymeric formula

300-1800 ml daily

4/4

Paediatric population

      

Hanai et al. [20]

95

32

Oral/NG

elemental

>900 calories daily

20/32 (62.5%)

Adults

      

Duncan et al.

48

15

Oral/NG

Polymeric or elemental

240-1000 ml

9/15

Paediatric population

      
  1. *Relapse rates at 1.5 years.