Table 5 Characteristics of genes and polymorphisms → patients (Pts) with non-alcoholic liver failure
Gene | Allele | rs number | Wild type genotype | Heterozygote genotype | Homozygote mutation | Pts |
|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | ||||
IL23R | G/A | 11209026 | 138 (93) | 11 (7) | 149 | |
IL18 RAP | A/G | 917997 | 75 (51) | 61 (41) | 12 (8) | 148 |
Card9 | G/A | 4077515 | 59 (40) | 67 (45) | 22 (15) | 148 |
NOD2 | C/T | 2066844 | 128 (86) | 21 (14) | 149 | |
NOD2 | G/C | 2066845 | 138 (81) | 22 (13) | 11 (6) | 171 |
NOD2 | -/C | 2066847 | 145 (97) | 3 (2) | 1 (1) | 149 |
TLR1 | G/C | 5743611 | 82 (55) | 56 (38) | 11 (7) | 149 |
TLR4 299 | G/A | 4986790 | 128 (86) | 19 (13) | 2 (1) | 149 |
TLR4 399 | G/A | 4987233 | 130 (87) | 18 (12) | 1 (1) | 149 |
TLR9 1237 | C/T | 5743836 | 50 (34) | 68 (46) | 29 (20) | 147 |
TLR9 1486 | T/C | 187084 | 90 (61) | 47 (32) | 10 (7) | 147 |
NQO1 609 | C/T | 1800566 | 92 (62) | 47 (31) | 10 (7) | 149 |
CYP1B1 432 | G/C | 1056836 | 59 (40) | 63 (42) | 26 (18) | 148 |
MTHFR 677 | T/C | 1801133 | 58 (39) | 66 (45) | 23 (16) | 147 |
MTHFR 1298 | C/A | 1801131 | 67 (53) | 42 (33) | 18 (14) | 127 |