Table 4 Characteristics of genes and polymorphisms → patients (Pts) with alcoholic liver failure
Gene | Allele | rs number | Wild type genotype | Heterozygote genotype | Homozygote mutation | Pts |
|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | ||||
IL23R | G/A | 11209026 | 44 (85) | 8 (15) | 52 | |
IL18 RAP | A/G | 917997 | 25 (48) | 23 (44) | 4 (8) | 52 |
CARD9 | G/A | 4077515 | 21 (40) | 23 (44) | 8 (15) | 52 |
NOD2 | C/T | 2066844 | 40 (77) | 12 (23) | 52 | |
NOD2 | G/C | 2066845 | 48 (80) | 10 (17) | 2(3) | 60 |
NOD2 | -/C | 2066847 | 47 (90) | 4 (8) | 1 (2) | 52 |
TLR1 | G/C | 5743611 | 32 (62) | 14 (27) | 6 (12) | 52 |
TLR4 299 | G/A | 4986790 | 50 (96) | 1 (2) | 1 (2) | 52 |
TLR4 399 | G/A | 4987233 | 48 (92) | 3 (6) | 1 (2) | 52 |
TLR9 1237 | C/T | 5743836 | 16 (31) | 27 (53) | 8 (16) | 51 |
TLR9 1486 | T/C | 187084 | 31 (61) | 19 (37) | 1 (2) | 51 |
NQO1 609 | C/T | 1800566 | 41 (79) | 9 (17) | 2 (4) | 52 |
CYP1B1 432 | G/C | 1056836 | 16 (31) | 20 (39) | 15 (30) | 51 |
MTHFR 677 | T/C | 1801133 | 23 (45) | 22 (43) | 6 (12) | 51 |
MTHFR 1298 | C/A | 1801131 | 18 (41) | 23 (52) | 3 (7) | 44 |