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Table 1 Demographical characteristics of the study population

From: Management of the HBV reactivation in isolated HBcAb positive patients affected with Non Hodgkin Lymphoma

Variable Overall HBsAg positive HBsAg negative p
No. of patients 498 38 460 -
Age - Mean [±SD] 61,00 [±14,05] 55,42 [±13,62] 57,32 [±14,95] 0,45
Sex – M/F M: 54,40% - M: 57,89% M: 47,83% 0,23
F: 45,40% F: 42,11% F: 52,17%
No. of patients HBsAb + 90 [18,07%] 0 90 [19,56%] 0,003
No. of patients HBcAb +/ HBsAg - 134 [26,90%] 0 96 [20,86%] 0,002
No. of patients HBcAb - / HBsAg - 274 [55,03%] 0 274 [59,56%]  
Lymphoma type Indolent: 47,3% - Indolent: 33,35% - Indolent: 44,34% - 0,22
  Aggressive: 52,7% Aggressive: 66,65% Aggressive: 55,66% 0,22
Rituximab therapy Yes: 60,30% - Yes: 18 [47,37%] Yes 262 [56,95%] 0,25
No: 39,70% No: 20 [52,63%] No: 198 [43,04%]  
HBV reactivation 10 [2,01%] 0 10 [2,17%] 0,22
NUC profilaxys/rescue therapy 38/10 38/0 0/10 <0,0001
“Per year Incidence of reactivation” [mean ± SD] 1,71% 0 2,04% <0,0001
±2,43% ±2,97
Liver related decompensations/hospitalizations/deaths 0% 0% 0% -
  1. In the first column overall patients characteristics: HBV reactivation occurred in 2,01% of cases. In the second and third column demographical characteristics of HBsAg positive and negative patients, respectively. HBV reactivation occurred in HBsAg negative patients only, due to the NUC profilaxys performed in HBsAg positive patients [see Methods]. (Chi-square, Pearson corrected calculations for all variables, Age: student t-test).