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Table 5 Comparison of the clinical characteristics of chronic hepatitis C patients with or without hepatic steatosis (≥5%)

From: Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C

   Steatosis (<5%)    Steatosis (≥5%)   
   n = 59    n = 18   
Factor Mean or number Maximum Minimum Mean or number Maximum Minimum P value*
Age (years) 55.2 76 20 59.1 69 33 0.257
Sex (male/female) 26/33    5/13    0.217
Body mass index (kg/m2) 22.3 30.1 16.4 23.8 32.2 19.9 0.800
Platelet count (×104/μl) 18.3 41.9 7.4 17.1 36.2 5.4 0.434
Total cholesterol (mg/dl) 171.4 295 84 168.4 222 114 0.814
Albumin (g/dl) 4.3 5.1 3.3 4.0 4.9 2.9 0.023
ALT (IU/l) 63.1 244 13 69.1 191 20 0.125
γ-GTP (IU/l) 40.6 239 12 81.4 468 12 0.010
Diabetes (absent/present) 50/9    10/8    0.009
Fasting plasma glucose (mg/dl) 95.9 196 72 100.8 150 80 0.145
Hemoglobin A1c (%) 5.3 (n = 57) 7.6 4.6 5.6 7.1 4.7 0.084
Leptin (ng/ml) 7.0 21.8 1.0 9.6 17.3 3.5 0.006
Adiponectin (ng/ml) 9.3 27.3 1.1 8 26.1 1.7 0.493
Resistin (ng/ml) 8.1 27.6 2.5 9.9 17.5 4 0.042
AIM (μg/ml) 1.37 4.56 0.41 1.43 6.44 0.72 0.290
Hyaluronic acid (ng/ml) 71.9 (n = 57) 292.7 10 171.6 636.0 11.2 0.021
  1. *Calculated by Chi-square test for categorical variables or Mann–Whitney U test for continuous variables.
  2. ALT, alanine aminotransferase; γGTP, γ-glutamyl transpeptidase; HOMA-IR, homeostasis model assessment-insulin resistance; AIM, apoptosis inhibitor of macrophage.