TY - JOUR AU - Miner, Philip B. AU - Silberg, Debra G. AU - Ruth, Magnus AU - Miller, Frank AU - Pandolfino, John PY - 2014 DA - 2014/11/18 TI - Dose-dependent effects of lesogaberan on reflux measures in patients with refractory gastroesophageal reflux disease: a randomized, placebo-controlled study JO - BMC Gastroenterology SP - 188 VL - 14 IS - 1 AB - The γ-aminobutyric acid type B-receptor agonist lesogaberan (AZD3355) has been developed for use in patients with gastroesophageal reflux disease (GERD) symptoms despite proton pump inhibitor (PPI) therapy (partial responders). This study aimed to explore the dose–response effect of lesogaberan on reflux episodes in partial responders. SN - 1471-230X UR - https://doi.org/10.1186/1471-230X-14-188 DO - 10.1186/1471-230X-14-188 ID - Miner2014 ER -