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Table 3 Predictors of length of hospitalization

From: MELD score and antibiotics use are predictors of length of stay in patients hospitalized with hepatic encephalopathy

A. Overall cohort

 

Univariable analysis

Multivariable analysis

Change in length of stay (days)

p-value

Change in length of stay (days)

p-value

Gender (female)

5.1

<0.01

2.2

0.04

Age

  

.

.

≤29

Reference

.

30-49

-10.2

0.19

50-69

-12.5

0.06

≥70

-13.8

0.04

MELD score

    

≤10

Reference

.

Reference

.

11-20

-6.9

0.01

-5.4

<0.01

21-30

-1.8

0.59

-3.8

0.02

31-40

3.1

0.48

-2.9

0.15

>40

4.9

0.38

-2.5

0.33

Hepatitis B

-0.2

0.95

.

.

Hepatitis C

-6.1

<0.01

-3.1

<0.01

Alcohol

1.0

0.53

.

.

Non-alcoholic fatty liver disease

1.3

0.60

.

.

Autoimmune hepatitis

-1.4

0.73

.

.

PBC/PSC

3.1

0.50

.

.

Hemochromatosis

-2.1

0.67

.

.

Post-liver transplant complication

3.2

0.51

.

.

Cryptogenic/unspecified

6.1

<0.01

.

.

Reason of hospitalization

    

-HE

Reference

.

Reference

.

-Liver-related

9.8

<0.01

7.6

<0.01

-Non liver-related

12.9

<0.01

10.7

<0.01

Acute hepatitis

9.7

<0.01

.

.

TIPS

-3.5

<0.01

.

.

Prior HE

-3.7

0.01

.

.

Rifaximin

1.9

0.28

.

.

Use of other antibiotics

10.2

<0.01

10.5

<0.01

B. Survivors cohort

 

Univariable analysis

Multivariable analysis

Change in length of stay (days)

p-value

Change in length of stay (days)

p-value

Gender (female)

5.5

<0.01

3.4

0.01

Age

    

≤29

Reference

Ref

.

.

30-49

1.5

<0.01

50-69

3.2

<0.01

≥70

5.1

MELD score

    

≤10

Reference

Ref

Reference

Reference

11-20

-8.0

<0.01

-6.6

<0.01

21-30

-2.7

0.41

-5.1

<0.01

31-40

5.2

0.33

2.7

0.38

>40

15.6

0.13

3.0

0.52

Hepatitis B

-4.1

<0.01

.

.

Hepatitis C

-6.1

<0.01

-3.9

<0.01

Alcohol

3.2

0.04

.

.

Non-alcoholic fatty liver disease

2.7

0.30

.

.

Autoimmune hepatitis

-1.4

0.74

.

.

PBC/PSC

-8.2

0.01

-8.3

<0.01

Hemochromatosis

-0.8

0.86

.

.

Post-liver transplant complication

1.9

0.72

.

.

Cryptogenic/unspecified

6.0

0.01

.

.

Reason of hospitalization

    

-HE

Reference

Ref

Reference

Ref

-Liver-related

21.8

<0.01

10.3

<0.01

-Non liver-related

27.7

<0.01

15.9

<0.01

Acute hepatitis

16.0

<0.01

.

.

TIPS

-6.8

<0.01

-4.5

0.04

Prior HE

-2.9

0.04

.

.

Rifaximin

-0.45

0.81

.

.

Use of other antibiotics

9.4

<0.01

9.9

<0.01