A. Overall cohort | ||||
---|---|---|---|---|
Univariable analysis | Multivariable analysis | |||
Change in length of stay (days) | p-value | Change in length of stay (days) | p-value | |
Gender (female) | 5.1 | <0.01 | 2.2 | 0.04 |
Age | . | . | ||
≤29 | Reference | . | ||
30-49 | -10.2 | 0.19 | ||
50-69 | -12.5 | 0.06 | ||
≥70 | -13.8 | 0.04 | ||
MELD score | ||||
≤10 | Reference | . | Reference | . |
11-20 | -6.9 | 0.01 | -5.4 | <0.01 |
21-30 | -1.8 | 0.59 | -3.8 | 0.02 |
31-40 | 3.1 | 0.48 | -2.9 | 0.15 |
>40 | 4.9 | 0.38 | -2.5 | 0.33 |
Hepatitis B | -0.2 | 0.95 | . | . |
Hepatitis C | -6.1 | <0.01 | -3.1 | <0.01 |
Alcohol | 1.0 | 0.53 | . | . |
Non-alcoholic fatty liver disease | 1.3 | 0.60 | . | . |
Autoimmune hepatitis | -1.4 | 0.73 | . | . |
PBC/PSC | 3.1 | 0.50 | . | . |
Hemochromatosis | -2.1 | 0.67 | . | . |
Post-liver transplant complication | 3.2 | 0.51 | . | . |
Cryptogenic/unspecified | 6.1 | <0.01 | . | . |
Reason of hospitalization | ||||
-HE | Reference | . | Reference | . |
-Liver-related | 9.8 | <0.01 | 7.6 | <0.01 |
-Non liver-related | 12.9 | <0.01 | 10.7 | <0.01 |
Acute hepatitis | 9.7 | <0.01 | . | . |
TIPS | -3.5 | <0.01 | . | . |
Prior HE | -3.7 | 0.01 | . | . |
Rifaximin | 1.9 | 0.28 | . | . |
Use of other antibiotics | 10.2 | <0.01 | 10.5 | <0.01 |
B. Survivors cohort | ||||
Univariable analysis | Multivariable analysis | |||
Change in length of stay (days) | p-value | Change in length of stay (days) | p-value | |
Gender (female) | 5.5 | <0.01 | 3.4 | 0.01 |
Age | ||||
≤29 | Reference | Ref | . | . |
30-49 | 1.5 | <0.01 | ||
50-69 | 3.2 | <0.01 | ||
≥70 | 5.1 | |||
MELD score | ||||
≤10 | Reference | Ref | Reference | Reference |
11-20 | -8.0 | <0.01 | -6.6 | <0.01 |
21-30 | -2.7 | 0.41 | -5.1 | <0.01 |
31-40 | 5.2 | 0.33 | 2.7 | 0.38 |
>40 | 15.6 | 0.13 | 3.0 | 0.52 |
Hepatitis B | -4.1 | <0.01 | . | . |
Hepatitis C | -6.1 | <0.01 | -3.9 | <0.01 |
Alcohol | 3.2 | 0.04 | . | . |
Non-alcoholic fatty liver disease | 2.7 | 0.30 | . | . |
Autoimmune hepatitis | -1.4 | 0.74 | . | . |
PBC/PSC | -8.2 | 0.01 | -8.3 | <0.01 |
Hemochromatosis | -0.8 | 0.86 | . | . |
Post-liver transplant complication | 1.9 | 0.72 | . | . |
Cryptogenic/unspecified | 6.0 | 0.01 | . | . |
Reason of hospitalization | ||||
-HE | Reference | Ref | Reference | Ref |
-Liver-related | 21.8 | <0.01 | 10.3 | <0.01 |
-Non liver-related | 27.7 | <0.01 | 15.9 | <0.01 |
Acute hepatitis | 16.0 | <0.01 | . | . |
TIPS | -6.8 | <0.01 | -4.5 | 0.04 |
Prior HE | -2.9 | 0.04 | . | . |
Rifaximin | -0.45 | 0.81 | . | . |
Use of other antibiotics | 9.4 | <0.01 | 9.9 | <0.01 |