Occurrence of Helicobacter pyloriand Epstein-Barr virus infection in endoscopic and gastric cancer patients from Northern Brazil

Table 2 Clinicopathological features, H. pylori and EBV infection in gastritis samples of adults patients

Variable	H. pylori			CagA			EBV
Variable	Negative	Positive	p-value	Negative^c	Positive	p-value	Negative	Positive	p-value
Age (Mean ± SD)	35.58 ± 7.82	45.00 ± 10.89	0.011*	37.6 ± 7.67	44.92 ± 11.75	0.039*	42.24 ± 11.14	39.50 ± 3.54	0.733
Gender [N(%)]
Female	3 (21.4)	11 (78.6)	0.410^a	5 (35.7)	9 (64.3)	0.915^a	14 (100)	0 (0)	0.999^a
Male	9 (36.0)	16 (64.0)		10 (40.0)	15 (60.0)		23 (92.0)	2 (8.0)
Histological subtype [N(%)]
Mild	7 (36.8)	12 (63.2)	0.715^b	9 (47.4)	10 (52.6)	0.820^b	17 (89.5)	2 (10.5)	0.999^b
Moderate/Severe	5 (25.0)	15 (75.0)		6 (30.0)	14 (70.0)		20 (100)	0 (0)
EBV infection [N(%)]
Absent	12 (32.4)	25 (67.6)	0.999^b	14 (37.8)	23 (62.2)	0.810^b
Present	0 (0)	2 (100)		1 (50.0)	1 (50.0)

*Significant difference between groups, p < 0.05. ^ap value after adjustment for age; ^bp value after adjustment for age and gender; ^cNegative samples for H. pylori and samples with H. pylori infection but without CagA virulence factor; EBV: Epstein-Barr virus; SD: standard deviation.

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