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Table 1 Clinicopathological features, H. pylori and EBV infection in gastritis samples of juvenile patients

From: Occurrence of Helicobacter pyloriand Epstein-Barr virus infection in endoscopic and gastric cancer patients from Northern Brazil

Variable H. pylori CagA EBV
Negative Positive p-value Negativec Positive p-value Negative Positive p-value
Age (years, Mean ± SD) 7.45 ± 3.88 12.19 ± 4.09 <0.001* 8.88 ± 4.49 12.45 ± 4.01 0.005* 9.96 ± 4.5 17 ± 1.41 0.033*
Gender [N(%)]          
Female 14 (42.4) 19 (57.6) 0.685a 23 (69.7) 10 (30.3) 0.096a 32 (97.0) 1 (3.0) 0.626a
Male 8 (40.0) 12 (60.0)   10 (50.0) 10 (50.0)   19 (95.0) 1 (5.0)  
Histological subtype [N(%)]          
Mild 16 (66.7) 8 (33.3) 0.026*b 20 (83.3) 4 (16.7) 0.108b 23 (95.8) 1 (4.2) 0.136b
Moderate/Severe 6 (20.7) 23 (79.3)   13 (44.8) 16 (55.2)   28 (96.6) 1 (3.4)  
EBV infection [N(%)]          
Absent 21 (41.2) 30 (58.8) 0.242b 31 (60.8) 20 (39.2) 0.998b    
Present 1 (50) 1 (50)   2 (100) 0 (0)     
  1. *Significant difference between groups, p < 0.05. ap value after adjustment for age; bp value after adjustment for age and gender; cNegative samples for H. pylori and samples with H. pylori infection but without CagA virulence factor; EBV: Epstein-Barr virus; SD: standard deviation.