Partial PPI responders | Treatment-naïve patients | ||
---|---|---|---|
GSRS domain/item | Before PPI treatment | After 2 weeks of PPI treatment | |
(n = 577a) | (n = 203) | (n = 203) | |
Reflux domain | 4.3 (4.2–4.4) | 3.5 (3.3–3.7) | 1.6 (1.5–1.7) |
Heartburn | 4.4 (4.3–4.5) | 3.7 (3.4–3.9) | 1.6 (1.5–1.8) |
Regurgitation | 4.2 (4.1–4.3) | 3.3 (3.0–3.5) | 1.6 (1.4–1.7) |
Abdominal pain domain | 3.4 (3.3–3.5) | 3.1 (3.0–3.3) | 2.0 (1.9–2.2) |
Abdominal pain | 4.0 (3.9–4.2) | 4.1 (3.9–4.3) | 2.3 (2.1–2.5) |
Hunger pains | 3.5 (3.3–3.6) | 3.0 (2.8–3.2) | 2.1 (1.9–2.3) |
Nausea | 2.7 (2.6–2.8) | 2.4 (2.1–2.6) | 1.7 (1.5–1.8) |
Indigestion syndrome | 3.7 (3.6–3.8) | 3.6 (3.4–3.7) | 2.5 (2.3–2.6) |
Rumbling | 3.3 (3.2–3.4) | 3.2 (3.0–3.4) | 2.3 (2.1–2.4) |
Bloated | 3.7 (3.5–3.8) | 3.8 (3.6–4.0) | 2.6 (2.4–2.8) |
Burping | 3.8 (3.7–3.9) | 3.4 (3.2–3.7) | 2.3 (2.1–2.4) |
Passing gas | 3.8 (3.7–4.0) | 3.8 (3.5–4.0) | 2.7 (2.5–2.9) |
Diarrhea syndrome | 2.1 (2.0–2.2) | 2.2 (2.0–2.4) | 1.7 (1.6–1.9) |
Diarrhea | 1.9 (1.8–2.0) | 2.2 (2.0–2.4) | 1.8 (1.6–1.9) |
Loose stools | 2.1 (1.9–2.2) | 2.2 (2.0–2.4) | 1.7 (1.6–1.8) |
Urgent need for bowel movement | 2.4 (2.3–2.5) | 2.3 (2.1–2.5) | 1.8 (1.6–1.9) |
Constipation syndrome | 2.5 (2.4–2.6) | 2.1 (1.9–2.2) | 1.8 (1.6–1.9) |
Constipation | 2.4 (2.3–2.6) | 1.9 (1.7–2.1) | 1.7 (1.5–1.8) |
Hard stools | 2.2 (2.1–2.4) | 1.9 (1.8–2.1) | 1.6 (1.5–1.8) |
Feeling of incomplete bowel movement | 2.7 (2.6–2.9) | 2.4 (2.2–2.6) | 2.0 (1.8–2.2) |