Skip to main content

Advertisement

Table 3 Histological characteristics of NAFLD- and AFLD group at index biopsy

From: Long term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver disease

  NAFLD group AFLD group p-value
n (%) n (%)
Steatosis    
1 (5-33%) 77 (51) 37 (39) NS
2 + 3 (≥33%) 74 (49) 57 (61) NS
Lobular inflammation    
0 + 1 (no foci or <2 foci/200x) 99 (66) 43 (46) 0.003
2 + 3 (2–4 foci or >4 foci/200x) 52 (34) 51 (54) 0.003
Ballooning    
0 + 1 (none or few balloon cells) 139 (92) 90 (96) NS
2 (many cells) 12 (8) 4 (4) NS
Fibrosis    
0 + 1 + 1A + 1B + 1C (none to mild fibrosis) 120 (79) 61 (65) 0.02
2 + 3 + 4 (moderate to severe) 31 (21) 33 (35) 0.02
NAS score    
<3 68 (45) 22 (23) 0.001
3-4 47 (31) 35 (37) NS
≥5 31 (21) 35 (37) 0.007