Advertisement
Table 3 Histological characteristics of NAFLD- and AFLD group at index biopsy
| NAFLD group | AFLD group | p-value | |
|---|---|---|---|
| n (%) | n (%) | ||
| Steatosis | |||
| 1 (5-33%) | 77 (51) | 37 (39) | NS |
| 2 + 3 (≥33%) | 74 (49) | 57 (61) | NS |
| Lobular inflammation | |||
| 0 + 1 (no foci or <2 foci/200x) | 99 (66) | 43 (46) | 0.003 |
| 2 + 3 (2–4 foci or >4 foci/200x) | 52 (34) | 51 (54) | 0.003 |
| Ballooning | |||
| 0 + 1 (none or few balloon cells) | 139 (92) | 90 (96) | NS |
| 2 (many cells) | 12 (8) | 4 (4) | NS |
| Fibrosis | |||
| 0 + 1 + 1A + 1B + 1C (none to mild fibrosis) | 120 (79) | 61 (65) | 0.02 |
| 2 + 3 + 4 (moderate to severe) | 31 (21) | 33 (35) | 0.02 |
| NAS score | |||
| <3 | 68 (45) | 22 (23) | 0.001 |
| 3-4 | 47 (31) | 35 (37) | NS |
| ≥5 | 31 (21) | 35 (37) | 0.007 |
